Therapeutic suppression of specific immune response by administration of oligomeric forms of antigen of controlled chemistry
US6375951B1 · kind B1 · utility
3Cited by
8References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 12, 1995 |
| Grant date | Apr 23, 2002 |
| Priority date | — |
| Expiry date | May 12, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/6093
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention features a non-immunogenic construct for reducing a non-primary antibody response to an epitope of a T-dependent antigen. The construct is free of high molecular weight immunostimulatory molecules and contains copies of the epitope which bind to a B cell membrane immunoglobulin receptor specific for the epitope but fail to form an imnunon.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.