Modified SELEX processes without purified protein
US6376190B1 · kind B1 · utility
71Cited by
16References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 22, 2000 |
| Grant date | Apr 23, 2002 |
| Priority date | — |
| Expiry date | Sep 22, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6811
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention is directed towards a method for obtaining nucleic acid ligands against target proteins without directly purifying the target proteins. The method used in the invention is called SELEX, which is an acronym for Systematic Evolution of Ligands by EXponential enrichment. The nucleic acid ligands of the invention are useful as diagnostic and therapeutic agents for diseases in which the targets proteins play a causative role.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.