Lipid complexes of APO A-1 agonist compounds

US6376464B1 · kind B1 · utility

Assignee

• Esperion Therapeutics, Inc. · US

Inventors

• Jean-Louis Dasseux · Mannheim, DE
• Renate Sekul · Ladenburg, DE
• Klaus Büttner · Epfenbach, DE
• Isabelle Cornut · Edingen-Neckarhausen, DE
• Günther Metz · Edingen-Neckarhausen, DE
• Jean Dufourcq · Pessac, FR

Key dates

• Filing date: Dec 1, 1999
• Grant date: Apr 23, 2002
• Expiry date: Dec 1, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K7/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.