Patent · US Expired

Amide derivatives as inhibitors of matrix metalloproteinases, TNF-&agr;, and aggrecanase

US6376665B1 · kind B1 · utility

8Cited by

1References

23Claims

0Family size

Inventors

Jingwu Duan · Yardley, US
Carl P. Decicco · New Hope, US
David J. Nelson · Newark, US
Chu-Biao Xue · Hockessin, US

Key dates

Filing date	Mar 31, 2000
Grant date	Apr 23, 2002
Priority date	—
Expiry date	Mar 31, 2020

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C2601/08
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present application describes novel amides and derivatives thereof of formula I: or pharmaceutically acceptable salt forms thereof, wherein these compounds are useful as inhibitors of matrix metalloproteinases, TNF-&agr;, and aggrecanase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.