Biodegradable glass compositions and methods for radiation therapy
US6379648B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 1, 1999 |
| Grant date | Apr 30, 2002 |
| Priority date | — |
| Expiry date | Feb 1, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC03C2213/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A nonradioactive glass in particulate form adapted for radiation therapy in a mammal comprise a biodegradable rare earth-lithium borate glass material of a specified composition which, upon being subjected to an effective amount of neutron irradiation, will produce a beta or gamma emitting radioisotope, the radioisotope being distributed throughout the glass material, the glass upon being introduced into a body fluid for radiation therapy being adapted to react therewith causing the radioisotope to form an insoluble compound on the surface of the glass material which is retained in the glass material and thereby prevented from escaping from the treatment site. Radioactive glasses and methods for carrying out radiation therapy with such radioactive glasses are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.