Methods for treatment of multiple sclerosis using peptide analogs of human myelin basic protein
US6379670B1 · kind B1 · utility
Assignees
Inventors
Key dates
| Filing date | Aug 19, 1999 |
| Grant date | Apr 30, 2002 |
| Priority date | — |
| Expiry date | Aug 19, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed toward peptide analogs of human myelin basic protein. The peptide analog is at least seven amino acids long and derived from residues 83 to 99 of human myelin basic protein. The analogs are altered from the native sequence at least at positions 91, 95, or 97. Additional alterations may be made at other positions. Pharmaceutical compositions containing these peptide analogs are provided. The peptide analogs are useful for treating multiple sclerosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.