Method for selecting compounds for treating ischemia-related cellular damage
US6379882B1 · kind B1 · utility
20Cited by
9References
13Claims
0Family size
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Key dates
| Filing date | Sep 10, 1999 |
| Grant date | Apr 30, 2002 |
| Priority date | — |
| Expiry date | Sep 10, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2510/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of screening for and treating subjects with a therapeutically effective amount of a compound that is effective in reducing cellular damage related to an ischemic condition, such as stroke or glaucoma. Test compounds are selected and therapeutically effective amount determined based on the relative efficacy of test compounds in preventing cell death in primary cultures of excitable cells, such as retinal ganglion cells, in vitro.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.