Diagnostic method using expression of MN/CA9 protein in AGUS Pap smears
US6379907B1 · kind B1 · utility
1Cited by
14References
9Claims
0Family size
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Key dates
| Filing date | Dec 15, 1999 |
| Grant date | Apr 30, 2002 |
| Priority date | — |
| Expiry date | Dec 15, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K16/3069
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Determining the presence of cancerous or pre-cancerous cervical lesions from AGUS-diagnosed Pap smear cells by observing the distribution of MN/CA9 antigen expressed on atypical or normal cells and diagnosing (a) significant lesions when MN/CA9 antigen is observed on atypical cells, (b) low grade lesions when MN/CA9 antigen is absent from atypical cells but is present on normal endocervical cells, and (c) a benign condition when MN/CA9 antigen is absent from both atypical cells and normal endocervical cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.