Chip-based isothermal amplification devices and methods
US6379929B1 · kind B1 · utility
632Cited by
14References
48Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 19, 1997 |
| Grant date | Apr 30, 2002 |
| Priority date | — |
| Expiry date | Nov 19, 2017 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2400/0688
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Disclosed are methods and compositions for isothermal amplification of nucleic acids in a microfabricated substrate. Methods and compositions for the analysis of isothermally amplified nucleic acids in a microfabricated substrate are disclosed as well. The microfabricated substrates and isothermal amplification and detection methods provided are envisioned for use in various diagnostic methods, particularly those connected with diseases characterized by altered gene sequences or gene expression.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.