Selected insect cell line clones providing increased yield of baculoviruses and gene expression products from recombinant baculoviruses
US6379958B1 · kind B1 · utility
1Cited by
1References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 24, 2000 |
| Grant date | Apr 30, 2002 |
| Priority date | — |
| Expiry date | May 24, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/948
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Three new insect cell lines have been established and characterized. The cloned cell lines are derived from IPLB-Sf-21AE and can grow in serum-free medium. When infected with baculovirus, the cell lines of the invention produce large quantities of baculovirus. Infection with recombinant baculovirus yields large quantities of expressed functional protein. In particular, cell lines deposited in ATCC as PTA-22O7, PTA-2206 and PTA-2205.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.