Evolution of whole cells and organisms by recursive sequence recombination
US6379964B1 · kind B1 · utility
210Cited by
77References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 15, 1999 |
| Grant date | Apr 30, 2002 |
| Priority date | — |
| Expiry date | Jul 15, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2217/05
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.