Treatment for dermal skin atrophy using thyroid hormone compounds or thyroid hormone-like compounds
US6380255B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Jul 14, 2000 |
| Grant date | Apr 30, 2002 |
| Priority date | — |
| Expiry date | Jul 14, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61Q19/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to a method for treating dermal atrophy of the skin. The method of the invention includes applying a composition to the skin of a mammal suffering from dermal atrophy of the skin, and comprising at least one thyroid hormone compound or thyroid hormone-like compound together with a pharmacologically acceptable base suitable for topical application, wherein the thyroid hormone compound or the thyroid hormone-like compound binds to TR-&agr; or TR-&bgr; with an equilibrium dissociation constant, Kd, of at least 10−5 M. The invention is also directed to an article of manufacture comprising packaging material and a pharmaceutical agent contained within the packaging material, wherein the pharmaceutical agent is therapeutically effective for treating dermal atrophy of the skin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.