Human DNA mismatch repair proteins
US6380369B1 · kind B1 · utility
23Cited by
5References
62Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 23, 1994 |
| Grant date | Apr 30, 2002 |
| Priority date | — |
| Expiry date | Aug 23, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/47
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention discloses three human DNA repair proteins and DNA (RNA) encoding such proteins. The DNA repair proteins which may be produced by recombinant DNA techniques. One of the human DNA repair proteins, hMLH1, has been mapped to chromosome 3 while hMLH2 has been mapped to chromosome 2 and hMLH3 has been mapped to chromosome 7. The polynucleotide sequences of the DNA repair proteins may be used for diagnosis of a hereditary susceptibility to cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.