Patent · US Expired

Chromatographic purification and separation process for mixtures of nucleic acids

US6383393B1 · kind B1 · utility

81Cited by

4References

23Claims

0Family size

Assignee

QIAGEN GmbH · DE

Inventors

Metin Colpan · Essen, DE
Joachim Schorr · Düsseldorf, DE
Ralf Herrmann · Königs Wusterhausen, DE
Petra Feuser · Cologne, DE

Key dates

Filing date	Mar 15, 1996
Grant date	May 7, 2002
Priority date	—
Expiry date	Mar 15, 2016

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N15/101
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A method for the purification and separation of nucleic acid mixtures by chromatography including adsorbing the nucleic acids to be separated and purified from a solution with a high concentration of salts (ionic strength) and/or a high concentration of alcohol on a substrate and subsequent desorbing from the substrate by means of a solution with lower concentration of salts (ionic strength).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.