Sustained-release microgranules containing diltiazem as active principle

US6383516B1 · kind B1 · utility

Assignee

• SOCIETE LABORATOIRES DES PRODUITS ETHIQUES ETHYPHARM · FR

Inventors

• Patrice Debregeas · Paris, FR
• Gerard Leduc · Nemours, FR
• Pascal Oury · Le Chesnay, FR
• Pascal Suplie · Montaure, FR

Key dates

• Filing date: Jan 11, 2001
• Grant date: May 7, 2002
• Expiry date: Jan 11, 2021

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P9/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel forms of sustained-release microgranules (LP) containing diltiazem are disclosed. The microgranules consist of a neutral granular carrier coated with an active layer including diltiazem or a pharmaceutically acceptable salt thereof as the active principle, a surfactant and a binder, and an outer layer providing sustained release of the active principle (layer LP).