Wondonin A and process for preparing the same
US6383521B1 · kind B1 · utility
1Cited by
4References
5Claims
0Family size
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Key dates
| Filing date | Apr 20, 2001 |
| Grant date | May 7, 2002 |
| Priority date | — |
| Expiry date | Apr 20, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides Wondonin A of general formula (I), which is extracted from a two-sponge association of phylum Porifera (sponge) and has antiangiogenic activity, and a process for preparing the same. Wondonin A has no cytotoxicity, but has an inhibitory activity against angiogenesis which is one of the crucial mechanisms of cancer cell metastasis, thus, it can be applied not only as an anticancer drug but also as a therapeutic agent of angiogenesis-associated diseases such as cardiac ischemia, rheumatoid arthritis, and diabetes mellitus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.