Methods of screening for pharmacologically active compounds for the treatment of tumour diseases
US6383733B1 · kind B1 · utility
17Cited by
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14Claims
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Key dates
| Filing date | Feb 16, 1999 |
| Grant date | May 7, 2002 |
| Priority date | — |
| Expiry date | Feb 16, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Pharmaceutical compositions containing as active compound a substance which inhibits the activity of TGF&bgr; on tumour cells of epithelial origin, for the treatment of epithelial, invasive tumour diseases which are characterized by a reversible transition of the cells from an epithelial, non-invasive state into a fibroblastoid, invasive state. The pharmaceutical composition contains a TGF&bgr; inhibitor, preferably combined with an Ras inhibitor. Process for screening substances for the treatment of epithelial, invasive tumour diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.