Family of immunoregulators designated leukocyte immunoglobulin-like receptors (LIR)
US6384203B1 · kind B1 · utility
16Cited by
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18Claims
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Key dates
| Filing date | May 12, 1999 |
| Grant date | May 7, 2002 |
| Priority date | — |
| Expiry date | May 12, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A new family of immunoreceptor molecules of the immunoglobulin superfamily, (LIR) polypeptides is described. Disclosed are sequences encoding LIR family members and their deduced amino acid sequences, polypeptides encoded by DNA that hybridizes to defined nucleotide sequences, processes for producing polypeptides of the LIR family, and specific antibodies directed against LIR polypeptides. LIR family members can be used to treat autoimmune diseases and disease states associated with suppressed immune function.
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