N-benzenesulfonyl-L-proline compounds, preparation method and method for using the compounds in therapy
US6384222B1 · kind B1 · utility
1Cited by
1References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 27, 1999 |
| Grant date | May 7, 2002 |
| Priority date | — |
| Expiry date | Dec 27, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds selected from the group consisting of:(i) the compounds of the formula  in which X is a halogen atom, A is a group—NH—(CH2)n—NH—CO—, —NH—CH2— orQ is a group R1 is hydrogen, halogen, C1-C3 alkyl or C1-C5 1-oxoalkyl, R2 is H or OH and n is 2, 3 or 4; and(ii) their addition salts.It further relates to the process for their preparation and to their use in therapeutics, especially for combating pathological conditions involving bradykinin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.