Process for preparing cis- aminochromanols
US6384244B2 · kind B2 · utility
1Cited by
3References
30Claims
0Family size
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Key dates
| Filing date | May 11, 2001 |
| Grant date | May 7, 2002 |
| Priority date | — |
| Expiry date | May 11, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D311/68
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
cis-aminochromanols are obtained in high yield and with high selectivity over their trans counterparts by hydrogenating the corresponding oximes in the presence of a catalyst and an acid selected from HBr, HCl, and organic sulfonic acid. The cis-aminochromanols can be employed as intermediates in the production of HIV protease inhibitors which are useful for treating HIV infection and AIDS.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.