Measuring device and the use thereof

US6384912B1 · kind B1 · utility

Assignee

• Novartis AG · CH

Inventors

• Gerolf Kraus · Kandern, DE
• Michael Pawlak · Laufenbürg, DE
• Gert Ludwig Duveneck · Bad Krozingen, DE
• Peter Oroszlan · Basel, CH
• Andreas Helg · Möhlin, CH
• Alfredo Emilio Bruno-Raimondi · Biel-Benken, CH

Key dates

• Filing date: Dec 22, 2000
• Grant date: May 7, 2002
• Expiry date: Dec 22, 2020

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2021/0346
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

A device has a planar optical waveguide, including a transparent carrier (40) and a wave-guiding layer (41), wherein the waveguide at least has a diffractive element (42) for coupling excitation radiation into the wave-guiding layer. Located on the wave-guiding layer is a further, tightly sealing layer (43) made from a material which, at least at the support surface, is transparent both to the excitation radiation and to the evanescently excited radiation at least to the penetration depth of the evanescent field, and which, for an analysis sample, has, at least in a partial region of the guided excitation radiation, a cavity (45) which is open to the upper side or a cavity (6) which is closed to the upper side and connected by means of an inlet channel (2) and an outlet channel (3). The depth of the cavity corresponds at least to the penetration depth of the evanescent field, and the diffractive element (42) is fully covered by the material of the layer (43) at least in the coupling-in region of the excitation radiation.