Methods and devices for reducing the mineral content of vascular calcified lesions
US6387071B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Nov 18, 1998 |
| Grant date | May 14, 2002 |
| Priority date | — |
| Expiry date | Nov 18, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2017/22098
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Methods and devices are provided for at least reducing the mineral content of a vascular calcified lesion, i.e. a calcified lesion present on the vascular tissue of a host. In the subject methods, the local environment of the lesion is maintained at a subphysiologic pH for a period of time sufficient for the mineral content of the lesion to be reduced, e.g. by flushing the lesion with a fluid capable of locally increasing the proton concentration in the region of the lesion. Also provided are catheters for use in performing the subject methods, where the catheters at least include a first lumen capable of delivering fluid to a vascular site and a second lumen capable of removing fluid from a vascular site. The subject methods and devices find particular use in the treatment of vascular diseases associated with the presence of calcified lesions on vascular tissue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.