Intraoperative, intravascular and endoscopic tumor and lesion detection, biopsy and therapy
US6387350B2 · kind B2 · utility
117Cited by
18References
9Claims
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Key dates
| Filing date | Jul 8, 1999 |
| Grant date | May 14, 2002 |
| Priority date | — |
| Expiry date | Jul 8, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2123/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods are provided for close-range intraoperative, endoscopic and intravascular detection and treatment of lesions, including tumors and non-malignant lesions. The methods use antibody fragments or subfragments labeled with isotopic and non-isotopic agents. Also provided are methods for detection and treatment of lesions with photodynamic agents and methods of treating lesions with a protein conjugated to an agent capable of being activated to emit Auger electron or other ionizing radiation. Compositions and kits useful in the above methods are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.