Vaccines containing paucilsmellar lipid vesicles as immunological adjuvants
US6387373B1 · kind B1 · utility
31Cited by
15References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 24, 1997 |
| Grant date | May 14, 2002 |
| Priority date | — |
| Expiry date | Apr 24, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2760/16234
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention features an adjuvanted vaccine, and methods for preparing an adjuvanted vaccine, preferably for immunizing against influenza, where the adjuvant is a lipid vesicle, and preferably is a nonphospholipid, paucilamellar lipid vesicle. The antigen may be encapsulated in the central cavity of the adjuvant, or mixed in solution with the adjuvant. Moreover, the adjuvant may carry a secondary adjuvant to further improve the immune response.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.