Patent · US Expired

Compositions containing at least one nucleic acid

US6387396B2 · kind B2 · utility

1Cited by
10References
24Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 6, 1999
Grant dateMay 14, 2002
Priority date
Expiry dateJan 6, 2019

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N15/88
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A composition containing a plurality of multicellular vesicles and at least one nucleic acid, at least one part of which is found included inside the multilamellar vesicles. Each of the vesicles is formed of a succession of lamellar bi-layers extending from each vesicle center to its periphery and including at least one surfactant agent. The bi-layers are concentric and are separated by a liquid medium. Such compositions can be used in pharmaceutics, particularly gene therapy, and in in vitro and in vivo transfection.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.