Assay for a regulator of cell cycle progression
US6387649B1 · kind B1 · utility
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2References
1Claims
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Key dates
| Filing date | Nov 14, 2000 |
| Grant date | May 14, 2002 |
| Priority date | — |
| Expiry date | Nov 14, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides nuclear localisation signals derived from the DP-3 and E2F-1 transcription factors and the use of these signals in assays for regulators of cell cycle progression. Such assays involve using the signals to direct a marker gene to the nucleus and determining whether the nuclear localisation of the marker is disrupted by the presence of a putative regulator.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.