Method of making a vaccine for anthrax

US6387665B1 · kind B1 · utility

Assignee

• The United States of America as represented by the Secretary of the Army · US

Inventors

• Bruce Ivins · Frederick, US
• Patricia Worsham · Jefferson, US
• Arthur M. Friedlander · Gaithersburg, US
• Joseph W. Farchaus · Frederick, US
• Susan L. Welkos · Frederick, US

Key dates

• Filing date: Mar 7, 2000
• Grant date: May 14, 2002
• Expiry date: Mar 7, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12R2001/07
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

A method of making a vaccine for anthracis that inolves a bacterial expression system and production and use of protective antigen (PA) against Bacillus anthracis. The PA immunogen is useful in a vaccine against human anthrax. The PA can be produced by an asporogenic organism which produces the desired antigen, which is then harvested from the supernatant.