Electrical impedance tomography to control electroporation
US6387671B1 · kind B1 · utility
176Cited by
4References
15Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 19, 2000 |
| Grant date | May 14, 2002 |
| Priority date | — |
| Expiry date | Jul 19, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12M35/02
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Images created by electrical impedance tomography (EIT) are used to adjust one or more electrical parameters and obtain a desired degree of electroporation of cells in tissue. The parameters include current, voltage and a combination thereof. The cells are subjected to conditions such that they become permeabilized but are preferably not subjected to conditions which result in irreversible pore formation and cell death. The electroporation can analyze cell membranes, diagnose tissues and the patient as well as to move materials into and out of cells in a controlled manner.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.