Methods and compositions for identifying a polynucleotide encoding a protease
US6387686B2 · kind B2 · utility
3Cited by
5References
51Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 23, 2001 |
| Grant date | May 14, 2002 |
| Priority date | — |
| Expiry date | Feb 23, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/13022
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods are disclosed whereby protease activity is directly linked to delivery of a transferable label to a target cell which expresses a protease, via fusion of viral display packages comprising the transferable label with the target cell. The methods can be used, inter alia, to identify proteases, including previously undiscovered proteases or variants of known proteases which may have altered substrate specificity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.