Patent · US Expired

4-heteroaryl-tetrahydroquinolines and their use as inhibitors of the cholesterin-ester transfer protein

US6387929B1 · kind B1 · utility

5Cited by

0References

8Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Jurgen Stoltefuss · Haan, DE
Michael Logers · Wuppertal, DE
Gunter Schmidt · Houghton, US
Arndt Brandes · Wuppertal, DE
Carsten Schmeck · Wuppertal, DE
Klaus-Dieter Bremm · Recklinghausen, DE
Hilmar Bischoff · Wuppertal, DE
Delf Schmidt · Wuppertal, DE

Key dates

Filing date	Mar 10, 2000
Grant date	May 14, 2002
Priority date	—
Expiry date	Mar 10, 2020

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D409/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Hetero-tetrahydroquinolines can be prepared either by condensing correspondingly substituted hetero-tetrahydroquinoline aldehydes with the desired substituent or by reducing the corresponding keto-substituted hetero-tetrahydroquinolines, followed by introduction of the desired substituent by customary methods. The hetero-tetrahydroquinolines are suitable for use as active compounds in medicaments, in particular in medicaments for treating artheriosclerosis and dyslipidaemias.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.