Heteroaryl-substituted quinolin-2-one derivatives useful as anticancer agents
US6388092B2 · kind B2 · utility
11Cited by
3References
2Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 17, 2001 |
| Grant date | May 14, 2002 |
| Priority date | — |
| Expiry date | Apr 17, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compounds of formula 1 and pharmaceutically acceptable salts and solvates thereof wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, and Z are as defined herein. The invention also relates to pharmaceutical compositions comprising compounds of formula 1 and to methods of inhibiting abnormal cell growth, including cancer, in a mammal by administering compounds of formula 1 to the mammal. The invention also relates to intermediates and methods useful in synthesizing compounds of formula 1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.