Process for the preparation of &bgr; hydroxy-&dgr; lactone using novel intermediates
US6388097B1 · kind B1 · utility
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9Claims
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Key dates
| Filing date | Feb 15, 2001 |
| Grant date | May 14, 2002 |
| Priority date | — |
| Expiry date | Feb 15, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/1892
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a process for the preparation of optically active 6-hydroxymethyl-4-tert-butyldimethylsilyloxy)-(4S,6R)-tetrahydro-2H-2-pyranone (&bgr; Hydroxy &dgr; Lacone) and the compound 3-oxo-5-(tert.butyldimethylsilyloxy-(1S-5S)-cyclohexylacetate having the formula the compound 3-hydroxy-5-(tert,butyldimethylsilyloxy)-(3R,5S)-cyclohexan-1 having the formula
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.