Fluorination of ketoamides
US6388133B1 · kind B1 · utility
0Cited by
4References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 9, 1999 |
| Grant date | May 14, 2002 |
| Priority date | — |
| Expiry date | Dec 9, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C235/74
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the preparation of an N,N-disubstituted-2-fluoro-1,3-ketoamide having the formula RCO.CFR′CONR2″ comprises treating an N,N-disubstituted-1,3-ketoamide having the formula RCO.CHR′CONR2″ with elemental fluorine. The groups R, R′ and R″ are independently selected from alkyl, aryl, substituted aryl, cycloalkyl, and substituted cycloalkyl. The group R′ may also be nitro or chlorine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.