Detection of nucleic acid hybrids
US6391551B1 · kind B1 · utility
80Cited by
73References
122Claims
0Family size
Assignee
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Key dates
| Filing date | Aug 25, 1999 |
| Grant date | May 21, 2002 |
| Priority date | — |
| Expiry date | Aug 25, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6827
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Processes are disclosed using the depolymerization of a nucleic acid hybrid to qualitatively and quantitatively analyze for the presence of a predetermined endogenous nucleic acid. Applications of those processes include the detection of single nucleotide polymorphisms, identification of single base changes, speciation, determination of viral load, genotyping, medical marker diagnostics, and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.