Method to detect Dirofilaria immitis infection
US6391569B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 18, 1996 |
| Grant date | May 21, 2002 |
| Priority date | — |
| Expiry date | Sep 18, 2016 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/4353
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention includes a method to detect D. immitis infection in a host animal using a D. immitis Di33 protein to detect anti-D. immitis Di33 antibodies in a bodily fluid of the animal. Also included is a method to detect D. immitis infection in a host animal using a D. immitis anti-Di33 protein to detect Di33 proteins in a bodily fluid of the animal. The present invention also relates to D. immitis detection kits that include either a Di33 protein or an anti-Di33 antibody; such kits also include a composition to detect an immunocomplex between the anti-Di33 antibody and D. immitis Di33 protein. The present invention also includes Di33 proteins, nucleic acid molecules encoding such proteins, as well as recombinant molecules and recombinant cells comprising such nucleic acid molecules, and anti-Di33 antibodies. Also included are methods to produce such proteins, nucleic acid molecules and antibodies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.