Methods for detecting membrane derived caspase activity and modulators thereof
US6391575B1 · kind B1 · utility
4Cited by
1References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 5, 1999 |
| Grant date | May 21, 2002 |
| Priority date | — |
| Expiry date | Mar 5, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/96466
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided are methods for detecting membrane derived apoptotic activity. In one embodiment, the present invention provides methods for identifying membrane derived caspase activity. In other embodiments, drug discovery methods are provided for screening compounds that inhibit or enhance membrane derived caspase activity. In the various embodiments, heavy membrane fractions are utilized for the screening methodologies described herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.