Patent · US Expired

Method of producing antihypercholesterolemic agents

US6391583B1 · kind B1 · utility

18Cited by

15References

19Claims

0Family size

Assignee

Wisconsin Alumni Research Foundation · US

Inventors

Charles R. Hutchinson · Madison, US
Jonathan Kennedy · Grass Valley, US
Cheonseok Park · Seoul, KR

Key dates

Filing date	Dec 18, 1998
Grant date	May 21, 2002
Priority date	—
Expiry date	Dec 18, 2018

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12R2001/66
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A method of increasing the production of lovastatin or monacolin J in a lovastatin-producing or non-lovastatin-producing organism is disclosed. In one embodiment, the method comprises the steps of transforming an organism with the A. terreus D4B segment, wherein the segment is translated and where an increase in lovastatin production occurs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.