Expression-cloning method for identifying target proteins for eukaryotic tyrosine kinases and novel target proteins
US6391584B1 · kind B1 · utility
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14Claims
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Key dates
| Filing date | Mar 29, 1999 |
| Grant date | May 21, 2002 |
| Priority date | — |
| Expiry date | Mar 29, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/9121
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to a novel method, based on direct expression cloning, for identifying target proteins capable of binding to and/or serving as substrates for receptor or cytoplasmic tyrosine kinases. The present invention also relates to novel proteins identified using this method, and to methods for identifying compounds that disrupt the interaction of such novel proteins with the receptor or cytoplasmic tyrosine kinases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.