3,4-Dihydroquinoline derivatives as nitrogen monoxide synthase (NOS) inhibitors

US6391887B1 · kind B1 · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Stefan Jaroch · Berlin, DE
• Hartmut Rehwinkel · Berlin, DE
• Peter Holscher · Berlin, DE
• Detlev Sülzle · Berlin, DE
• Margrit Hillmann · Berlin, DE
• Gerardine Anne Burton · Berlin, DE
• Fiona Mcdougall McDonald · Berlin, DE

Key dates

• Filing date: Aug 14, 2000
• Grant date: May 21, 2002
• Expiry date: Aug 14, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D491/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to compounds of formula (I), as defined herein. The invention also relates to the use of the inventive compounds for treatment of a disease caused by the effects of nitrogen monoxide in pathological conditions.