Immunotoxins directed against malignant cells
US6395276B1 · kind B1 · utility
103Cited by
6References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 1, 1998 |
| Grant date | May 28, 2002 |
| Priority date | — |
| Expiry date | May 1, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to immunotoxins, that effectively kill malignant cells having a given surface marker and nucleic acid constructs encoding them. These reagents comprise a toxic moiety that is derived from a Rana pipiens protein having ribonucleolytic activity linked to an antibody capable of specific binding with a chosen tumor cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.