Patent · US Expired

Apparatus and method for preparing microparticles

US6395304B2 · kind B2 · utility

12Cited by

27References

23Claims

0Family size

Assignee

Alkermes Controlled Therapeutics, Inc. · US

Inventors

Shawn L. Lyons · Cincinnati, US
Steven G. Wright · Madeira, US

Key dates

Filing date	Apr 10, 2001
Grant date	May 28, 2002
Priority date	—
Expiry date	Apr 10, 2021

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T428/2985
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Apparatus and method for preparing microparticles. An emulsion is formed by combining two phases in a static mixing assembly. The static mixing assembly preferably includes a preblending static mixer and a manifold. The emulsion flows out of the static mixing assembly into a quench liquid whereby droplets of the emulsion form microparticles. The residence time of the emulsion in the static mixing assembly is controlled to obtain a predetermined particle size distribution of the resulting microparticles.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.