Method for the continuous microbiological production of polyhydroxy butyric acid
US6395520B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 3, 2000 |
| Grant date | May 28, 2002 |
| Priority date | — |
| Expiry date | Nov 3, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/822
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to the microbial synthesis of polyhydroxyalkanoic acids [PHA(B)] from substrates which have potential environmental toxicity and must therefore be detoxified and which, if capable of being utilized as a source of carbon and energy by microorganisms for growth and propagation, exhibit the phenomenon of substrate inhibition. According to the invention, a process for the continuous microbiological production of PHB is provided, which process is characterized in that strains of microorganisms known to be PHB producers are propagated chemo-statically at maximum heat production on substrates exhibiting growth inhibition in case of excess substrate, the maximum heat production corresponding to a maximum PHB content in the biomass being adjusted by means of the substrate flow rate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.