3,6-disubstituted penam sulfone derivatives
US6395726B1 · kind B1 · utility
2Cited by
6References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 24, 2000 |
| Grant date | May 28, 2002 |
| Priority date | — |
| Expiry date | Jan 24, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D499/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds are provided having the following formulae I and II: whereinn is 0 or 1 andwhen n=1, R is a 5 or 6 membered heterocyclic ring, hydroxy, halogen, oxo, carbamoyl, alkoxy, or disubstituted amino,when n=0, R is an ester, cyano or amide group;X is CH or NH;R3 is cyano, methoxy, or acetamido;R1 is hydrogen, alkyl, a negative charge, a cation selected from the group consisting of sodium, potassium and tetraalkylammonium and acyloxyalkyl, or alkoxycarbonyloxyalkyl; andR2 is hydrogen, acyl, trisubstituted silyl carbamoyl or an amino acid residue; or pharmaceutically acceptable salts thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.