Patent · US Expired

Nitriloxy derivatives of (R) and (S)-carnitine

US6395923B2 · kind B2 · utility

0Cited by

3References

5Claims

0Family size

Assignee

SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. · IT

Inventors

Oreste Piccolo
Roberto Castagnani · Recanati, IT
Paolo De Witt · Roma, IT

Key dates

Filing date	Mar 13, 2001
Grant date	May 28, 2002
Priority date	—
Expiry date	Mar 13, 2021

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B2200/07
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Carnitine derivatives of formula (I) are described in racemic and/or optically active form, as well as the process for their preparation and their use as pharmaceutical anti-angina active ingredients for the treatment of ischaemic heart disease. Also described is a process for producing the (R)-carnitine enantiomer from (S)-carnitine (or vice versa), using the derivatives of formula (I).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.