Enhancing expression of a silenced target sequence in plants using plant viral enhancers and amplicons
US6395962B1 · kind B1 · utility
14Cited by
11References
40Claims
0Family size
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Key dates
| Filing date | Jun 22, 1999 |
| Grant date | May 28, 2002 |
| Priority date | — |
| Expiry date | Jun 22, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/8216
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Compositions and methods for modulating gene expression in plants are provided. The methods comprise the use of a gene silencer (amplicon) in combination with an enhancer sequence (suppressor of co-suppression). Amplicons comprise a targeting sequence corresponding to the gene of interest, the target gene. The amplicon will direct gene silencing against a sequence with homology to the targeting sequence, (the target sequence). The amplicon may optionally comprise a promoter and a sequence that corresponds to at least a part of a viral genome.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.