Nucleic acids encoding neural/pancreatic receptor tyrosine phosphatase
US6399326B1 · kind B1 · utility
9Cited by
1References
15Claims
0Family size
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Key dates
| Filing date | Jun 27, 1997 |
| Grant date | Jun 4, 2002 |
| Priority date | — |
| Expiry date | Jun 27, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
We describe here a new class of protein tyrosine phosphatases (PTP), called “PTP-NP” (for neural and pancreatic) receptors. The sequence of an exemplary PTP-NP gene (SEQ ID No. 1) indicates it encodes a receptor type PTP (SEQ ID No. 2) with a single tyrosine phosphatase domain. Comparison of PTP-NP with the other known PTPs reveals a cysteine-conserved motif in the extracellular domain and, together with their homology in the phosphatase domain, this defines a new subclass of receptor type PTPs.
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