DNA sequences for matrix metalloproteases, their production and use

US6399348B1 · kind B1 · utility

Assignee

• MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN IN DER · DE

Inventors

• Horst Will · Berlin, DE
• Bernd Hinzmann · Berlin, DE

Key dates

• Filing date: Mar 8, 2000
• Grant date: Jun 4, 2002
• Expiry date: Mar 8, 2020

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

DNA sequences for human matrix metalloproteases are disclosed, as well as homologous DNA sequences homologous and derived therefrom. Also disclosed are the proteins and protein variants coded by these DNA sequences, there expression, preparation and use. The invention has applications in the fields of biomolecular, medical and pharmaceutical research, for medical diagnosis and therapy, and in the pharmaceutical and biotechnological industry.