Method of isolating receptor and ligand DNA
US6399386B1 · kind B1 · utility
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3References
4Claims
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Key dates
| Filing date | Feb 18, 2000 |
| Grant date | Jun 4, 2002 |
| Priority date | — |
| Expiry date | Feb 18, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are compositions and methods which are useful in the identification and isolation of components involved in transmembrane receptor-mediated signaling. Such components include the receptors themselves (e.g., tyrosine kinase receptors, cytokine receptors and tyrosine phosphatase receptors), as well as ligands which bind the receptors and modulators of the downstream intracellular catalytic event which characterizes receptor-mediated signalling. Two novel ligands for the FGF receptor and the nucleotide sequences encoding them are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.