Cyclic hexapeptides having antibiotic activity
US6399567B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 16, 1999 |
| Grant date | Jun 4, 2002 |
| Priority date | — |
| Expiry date | Jun 16, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to new polypeptide compounds represented by the following formula (I): whereinR1 is as defined in the description or a salt thereof which have antimicrobial activities (especially, antifungal activities), inhibitory activity on &bgr;-1,3-glucan synthase, to process for preparation thereof, to a pharmaceutical composition comprising the same, and to a method for the prophylactic and/or therapeutic treatment of infectious disease including Pneumocystis carinii infection (e.g., Pneumocystis carinii pneumonia) in a human being or an animal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.