Conjugates comprising galactose &agr;1,3 galactosyl epitopes and methods of using same
US6399578B1 · kind B1 · utility
7Cited by
18References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 8, 1999 |
| Grant date | Jun 4, 2002 |
| Priority date | — |
| Expiry date | Dec 8, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/18
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides conjugates useful for xenotransplantation which comprise a galactose &agr;1,3 galactosyl (&agr;Gal) epitope conjugated to a valency platform molecule, preferably a chemically defined valency platform molecule which allows precise valency. The invention also provides compositions comprising these conjugates, and methods (such as methods for inducing tolerance) using these conjugates and compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.